efflux system造句

• DcuC may therefore function as a succinate efflux system during anaerobic glucose fermentation.
• Arsenic efflux systems are found in nearly every organism and evolved to rid cells of this toxic metalloid.
• Efflux systems function via an energy-dependent mechanism ( active transport ) to pump out unwanted toxic substances through specific efflux pumps.
• Some efflux systems are drug-specific, whereas others may accommodate multiple drugs, and thus contribute to bacterial multidrug resistance ( MDR ).
• The ability of efflux systems to recognize a large number of compounds other than their natural substrates is probably because substrate recognition is based on receptor recognition.
• These efflux systems include members of the multidrug resistance protein family and the bacterial exchangers Acr3 and ArsB . ArsB can also be a subunit of the ArsAB As ( III )-translocating ATPase, an ATP-driven efflux pump.
• S110 provides some clues to the organism s metal tolerance by identifying key molecular machinery in processing metals such as the arsenic reductase complex ArsRBC, metal transporting P1-type ATPases and a chemiosmotic antiporter efflux system similar to CzcCBA of " Cupriavidus metallidurans ".
• Gram-negative bacteria are protected against toxic electrophilic compounds by glutathione-gated potassium efflux systems ( Kef ) that modulate cytoplasmic pH . Roosild et al . ( 2010 ) have elucidated the mechanism of gating through structural and functional analysis of the " E . coli"
• In bacterial efflux systems, certain substances that need to be extruded from the cell include surface components of the bacterial cell ( e . g . capsular polysaccharides, lipopolysaccharides, and teichoic acid ), proteins involved in bacterial pathogenesis ( e . g . hemolysis, heme-binding protein, and alkaline protease ), heme, hydrolytic enzymes, S-layer proteins, competence factors, toxins, antibiotics, bacteriocins, peptide antibiotics, drugs and siderophores.